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Tomorrow's health is... Defining a new possible.

Sr. Project Manager – Operations Transformation

Richmond, Virginia Job ID JR0138485 Category General Project Management, Business & Strategy Post Date Oct. 31, 2025
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McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Overview

As McKesson separates its Medical-Surgical business unit into a new independent entity, we are seeking a Project Manager to lead cross-functional efforts that support compliance and regulatory readiness. This role will focus on projects related to controlled substances and (Drug Supply Chain Security Act) DSCSA, ensuring that new operational capabilities meet legal and regulatory standards while legacy dependencies are responsibly retired. The ideal candidate brings deep experience in regulatory coordination, strong project leadership, and the ability to navigate complex stakeholder environments.

Key Responsibilities

  • Develop and manage detailed project plans, timelines, and resource allocations across compliance functions.
  • Identify and mitigate risks, manage interdependencies, and resolve issues related to regulatory obligations.
  • Facilitate cross-functional meetings and ensure stakeholder engagement across impacted teams.
  • Collaborate with the internal transformation office and external partners to ensure strategic alignment.
  • Provide regular updates to leadership and governance bodies on compliance progress and risks.
  • Lead planning and execution of compliance-related projects tied to the separation initiative.
  • Coordinate with legal, regulatory, and operational teams to ensure alignment with federal and state requirements.
  • Support audits, inspections, and readiness assessments for controlled substances and DSCSA compliance.
  • Maintain accurate documentation and reporting for regulatory workstreams.
  • Prepare and deliver presentations and reports for internal governance and external regulatory bodies.

We’re Looking for Someone Who:  

  • Thinks strategically and executes precisely – Connects business needs with operational realities and translates complex challenges into actionable plans 
  • Influences with clarity – Communicates effectively across all levels, helping teams align on priorities and drive momentum 
  • Is a compelling storyteller – Builds visually engaging and executive-ready PowerPoint decks that clearly communicate strategy, progress, and impact to drive buy-in and decision-making 
  • Is curious and resourceful – Asks thoughtful questions, explores new ideas, and thrives in ambiguity 
  • Acts with urgency – Moves projects forward despite obstacles, staying focused on outcomes 
  • Builds strong partnerships – Fosters collaboration, trust, and alignment across diverse teams 

Qualifications

  • 5+ years of experience in project management, preferably in compliance, regulatory affairs, or transformation initiatives.
  • Proven ability to lead cross-functional teams in a matrixed organization.
  • Strong understanding of DSCSA, controlled substance regulations, and healthcare compliance standards.
  • Excellent analytical, communication, and leadership skills.
  • Proficient in Smartsheet and Excel, with a strong ability to craft compelling narratives using PowerPoint.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$102,100 - $170,100

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees and is committed to a diverse and inclusive environment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age or genetic information. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

Join us at McKesson!

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McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

  • McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.
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  • McKesson job postings are posted on our career site: careers.mckesson.com.

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